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31.
Objectives: In China, both human urinary kallindinogenase (HUK) and 3-n-butylphthalide (NBP) are recommended for clinical use to improve cerebral blood circulation during an acute ischemic stroke (AIS). The objective was to evaluate the economic value of HUK vs NBP for patients with AIS from a Chinese payer’s perspective.

Methods: An economic evaluation based on data of patients who have been treated with either HUK (n?=?488) or NBP (n?=?885) from a prospective, phase IV, multi-center, clinical registry study (Chinese Acute Ischemic Stroke Treatment Outcome Registry, CASTOR) was conducted to analyze the cost and effectiveness of HUK vs NBP for AIS in China. Before the analysis, the patients were matched using propensity score. Both a cost-minimization analysis and a cost-effectiveness analysis were conducted to compare the matched pairs. A bootstrapping exercise was conducted for the matched arms to demonstrate the probability of one intervention being cost-effective over another for a given willingness-to-pay for an extra quality-adjusted life-year (QALY).

Results: After propensity score matching, 463 pairs were matched. The overall medical cost in the HUK arm is USD 2,701.20, while the NBP arm is USD 3,436.83, indicating HUK is preferred with cost-minimization analysis. Although the QALY gained in the HUK arm (0.77176) compared with the NBP arm (0.76831) is statistically insignificant (p?=?.4862), the cost-effectiveness analysis as exploratory analysis found that, compared with NBP, HUK is a cost-saving strategy with the lower costs of USD 735.63 and greater QALYs gained of 0.00345. Among the 5,000 bootstrapping replications, 100% indicates that HUK is cost-effective compared with NBP under a 1-time-GDP threshold; and 97.12% indicates the same under a 3-time-GDP threshold.

Conclusion: This economic evaluation study indicates that administrating HUK is a cost-saving therapy compared with NBP for managing blood flow during AIS in the Chinese setting.  相似文献   
32.
[目的]为了进一步提升农村产业融合发展效率,提升农业质量效益和竞争力、增强农村发展活力、促进农民持续增收,[方法]文章根据我国农村产业融合发展的投入产出指标数据,利用DEA方法对我国31个省(自治区、直辖市)农村产业融合效率进行了科学的分析与测算,[结果]研究表明,我国农村产业融发展的总体效率偏低。从综合效率看,仅有天津等7个省(自治区、直辖市)的综合效率值高于0. 5;从纯技术效率看,仅有江苏等8个省(自治区、直辖市)的纯技术效率高于0. 5;从规模效率看,西藏、甘肃、青海3个省(自治区)的规模效率低于0. 5。提升农村产业融合发展效率仍有较大的空间。[结论]应从进一步加大对农村产业融合发展的资金投入力度、着力优化农村产业融合发展的资金投入结构、建立农村产业融合发展效率考评制度等方面提升农村产业融合发展效率,促进农村产业融合快速发展。  相似文献   
33.
在互联网环境下,非营利组织纷纷建设门户网站加强与社会大众以及各利益相关方的沟通联系。随着非营利组织社会责任考量的日益重要,但目前对非营利组织通过网站履行社会责任的可行性评估一直处于空白状态,基于该视角,对中国17家最具有代表性的中国非营利组织进行了为期24天的网站检测,通过层次分析法对网站数据计算分析并进行网站排名。测评结果显示,目前中国优秀非营利组织在职能责任方面,依然存在网站更新频率低,活动相关性不足等问题,网站建设和运营方面仍有很大完善空间。  相似文献   
34.
[目的]在扶贫开发战略中成长起来的特色产业已经成为贫困地区经济发展和农民脱贫致富的支柱产业,特色产业的规模和经济效率直接决定着贫困地区脱贫致富能力。[方法]文章以茶叶、蔬菜代表武陵山片区湖北省恩施自治州扶贫产业,利用集中度指数、扩张弹性系数、单位面积的产值能力和产量能力以及单位产量的产值能力等指标进行扶贫产业发展的规模特征及其经济效率评价。[结果]“十一五”期间以来武陵山片区扶贫产业发展的产业地位逐渐提高、规模扩张优势显著、规模收益递增、投入规模扩张率高于产出规模扩张率、资源配置效率不断提高,比较经济效率差距持续扩大。[结论]扶贫产业亟待根据产业发展的生态化、集聚化和融合化等趋势,在规模扩张中强化特色产品的品质建设和效率优势品种生产专业化程度、提高生产技术水平以及完善产业化组织及其能力建设,提高扶贫产业的经济效率和致富能力。  相似文献   
35.
Online-to-offline (O2O) has become a rapidly growing e-commerce model worldwide, but the factors influencing consumers' purchase decision-making have not been examined well. After exploring the working mechanism of the O2O model, we extract eleven indexes of consumers' overall evaluation in the O2O model with Crawlzilla and R techniques. Social network analysis (SNA) is adopted to build social networks reflecting consumers' overall evaluation in the O2O model. Based on the modified social network and the extracted subgraph, this study (N = 768) reveals consumers' overall evaluation behavior patterns in the O2O model by calculating network density, central potential, edge betweenness. The results show that shoppers overall evaluate the eleven indexes, especially perceived product quality, online product price, promotion intensity, business reputation, and product brand, which reflects the significant associations between the indexes. Among all the eleven evaluation indexes, perceived product quality, online product price, and business reputation dominate consumers’ decision-making behavior. When making purchase decisions, consumers not only overall consider online product price, perceived product quality, and business reputation but also balance perceived product quality, business reputation, and promotion intensity. Finally, we make some suggestions on marketing strategy for e-commerce companies.  相似文献   
36.
Data envelopment analysis (DEA) is a non-parametric approach for measuring the relative efficiencies of peer decision making units (DMUs). In recent years, it has been widely used to evaluate two-stage systems under different organization mechanisms. This study modifies the conventional leader–follower DEA models for two-stage systems by considering the uncertainty of data. The dual deterministic linear models are first constructed from the stochastic CCR models under the assumption that all components of inputs, outputs, and intermediate products are related only with some basic stochastic factors, which follow continuous and symmetric distributions with nonnegative compact supports. The stochastic leader–follower DEA models are then developed for measuring the efficiencies of the two stages. The stochastic efficiency of the whole system can be uniquely decomposed into the product of the efficiencies of the two stages. Relationships between stochastic efficiencies from stochastic CCR and stochastic leader–follower DEA models are also discussed. An example of the commercial banks in China is considered using the proposed models under different risk levels.  相似文献   
37.
自然资源规划评估在实践探索中形成了一套“三期十步法”的评估模式。文章以总结国内外规划评估经验为基础,具体阐述自然资源“十三五”规划评估开展的基本内容和任务,并结合实践中存在的突出问题,提出完善“十四五”规划评估的建议:一是推动自然资源规划评估标准化建设;二是构建完善的评估数据信息系统;三是建立良好的评估运行监测机制;四是加大规划评估的宣传引导。  相似文献   
38.
将随机选出的混合型基金作为研究样本,采用DEA-Tobit二阶段模型进行研究.首先利用数据包络模型对样本进行绩效评估,在此基础上,利用Tobit模型研究相关指标对于基金绩效的影响机制.结果表明,基金本身所面临的风险收益因素以及基金经理团队稳定性对于基金绩效均具显著影响.最后结合实证结果就提升中国基金绩效提出相关的建议.  相似文献   
39.
文章构建了由31项指标组成的新型城镇化综合发展质量评价指标体系,运用AHP层次分析法和熵值法,选择19个国家级新区中2018年经济总量排名前十的新区进行定量对比分析,并结合民生幸福建设群众满意度问卷调查分析,对南京江北新区新型城镇化发展质量进行综合评价。研究表明:(1)南京江北新区新型城镇化整体发展处于中上游水平,与发达新区相比存在一定差距,产业结构亟需优化;(2)发展增长方式、资源利用率、环境保护类指标明显落后;(3)科教文卫、居民生活等指标具有比较优势。文章最后提出新型城镇化提升路径为加快生态环境和公共服务建设,积极提升科教和生态示范效应,做大做强主导产业,促进城乡特色均衡发展和推进以人为核心的新型城镇化。  相似文献   
40.
Given lags in the release of data, a central bank must ‘nowcast’ current gross domestic product (GDP) using available quarterly or higher frequency data to understand the current state of economic activity. This paper uses various statistical modelling techniques to draw on a large number of series to nowcast South African GDP. We also show that GDP volatility has increased markedly over the last 5 years, making GDP forecasting more difficult. We show that all the models developed, as well as the Reserve Bank's official forecasts, have tended to overestimate GDP growth over this period. However, several of the statistical nowcasting models we present in this paper provide competitive nowcasts relative to the official Reserve Bank and market analysts' nowcasts.  相似文献   
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